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Adaptive changes in the transcription factor HoxA-11 are essential for the evolution of pregnancy in mammals

Evolutionary change in gene regulation can result from changes in cis-regulatory elements, leading to differences in the temporal and spatial expression of genes or in the coding region of transcription factors leading to novel functions or both. Although there is a growing body of evidence supporti...

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Detalhes bibliográficos
Main Authors: Lynch, Vincent J., Tanzer, Andrea, Wang, Yajun, Leung, Frederick C., Gellersen, Birgit, Emera, Deena, Wagner, Gunter P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567470/
https://ncbi.nlm.nih.gov/pubmed/18809929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802355105
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