Translational bypassing without peptidyl-tRNA anticodon scanning of coding gap mRNA

Half the ribosomes translating the mRNA for phage T4 gene 60 topoisomerase subunit bypass a 50 nucleotide coding gap between codons 46 and 47. The pairing of codon 46 with its cognate peptidyl-tRNA anticodon dissociates, and following mRNA slippage, peptidyl-tRNA re-pairs to mRNA at a matched triple...

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Main Authors: Wills, Norma M, O'Connor, Michelle, Nelson, Chad C, Rettberg, Charles C, Huang, Wai Mun, Gesteland, Raymond F, Atkins, John F
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567401/
https://ncbi.nlm.nih.gov/pubmed/18772887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.170
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