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A mono-allelic bivalent chromatin domain controls tissue-specific imprinting at Grb10
Genomic imprinting is a developmental mechanism that mediates parent-of-origin-specific expression in a subset of genes. How the tissue specificity of imprinted gene expression is controlled remains poorly understood. As a model to address this question, we studied Grb10, a gene that displays brain-...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567399/ https://ncbi.nlm.nih.gov/pubmed/18650936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.142 |
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