Similarity of aberrant DNA methylation in Barrett's esophagus and esophageal adenocarcinoma

BACKGROUND: Barrett's esophagus (BE) is the metaplastic replacement of squamous with columnar epithelium in the esophagus, as a result of reflux. It is the major risk factor for the development of esophageal adenocarcinoma (EAC). Methylation of CpG dinucleotides of normally unmethylated genes i...

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Detalhes bibliográficos
Main Authors: Smith, Eric, De Young, Neville J, Pavey, Sandra J, Hayward, Nicholas K, Nancarrow, Derek J, Whiteman, David C, Smithers, B Mark, Ruszkiewicz, Andrew R, Clouston, Andrew D, Gotley, David C, Devitt, Peter G, Jamieson, Glyn G, Drew, Paul A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567345/
https://ncbi.nlm.nih.gov/pubmed/18831746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-7-75
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