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Demonstration of pyrimidine dimer-DNA glycosylase activity in vivo: bacteriophage T4-infected Escherichia coli as a model system.

An approach to the detection of pyrimidine dimer-DNA glycosylase activity in living cells is presented. Mutants of Escherichia coli defective in uvr functions required for incision of UV-irradiated DNA were infected with phage T4 denV+ or denV- (defective in the T4 pyrimidine dimer-DNA glycosylase a...

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Bibliographic Details
Published in:J Virol
Main Authors: Radany, E H, Friedberg, E C
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1982
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC256728/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7045391/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.41.1.88-96.1982
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