Identification of a gain-of-function mutation of the prolactin receptor in women with benign breast tumors

There is currently no known genetic disease linked to prolactin (Prl) or its receptor (PrlR) in humans. Given the essential role of this hormonal system in breast physiology, we reasoned that genetic anomalies of Prl/PrlR genes may be related to the occurrence of breast diseases with high proliferat...

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Main Authors: Bogorad, Roman L., Courtillot, Carine, Mestayer, Chidi, Bernichtein, Sophie, Harutyunyan, Lilya, Jomain, Jean-Baptiste, Bachelot, Anne, Kuttenn, Frédérique, Kelly, Paul A., Goffin, Vincent, Touraine, Philippe
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567233/
https://ncbi.nlm.nih.gov/pubmed/18779591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800685105
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