Blood-stage Plasmodium infection induces CD8(+) T lymphocytes to parasite-expressed antigens, largely regulated by CD8α(+) dendritic cells

Although CD8(+) T cells do not contribute to protection against the blood stage of Plasmodium infection, there is mounting evidence that they are principal mediators of murine experimental cerebral malaria (ECM). At present, there is no direct evidence that the CD8(+) T cells mediating ECM are paras...

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Detalhes bibliográficos
Main Authors: Lundie, Rachel J., de Koning-Ward, Tania F., Davey, Gayle M., Nie, Catherine Q., Hansen, Diana S., Lau, Lei Shong, Mintern, Justine D., Belz, Gabrielle T., Schofield, Louis, Carbone, Francis R., Villadangos, Jose A., Crabb, Brendan S., Heath, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567226/
https://ncbi.nlm.nih.gov/pubmed/18799734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806727105
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