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Direct characterization of amyloidogenic oligomers by single-molecule fluorescence

A key issue in understanding the pathogenic conditions associated with the aberrant aggregation of misfolded proteins is the identification and characterization of species formed during the aggregation process. Probing the nature of such species has, however, proved to be extremely challenging to co...

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Bibliografiske detaljer
Main Authors: Orte, Angel, Birkett, Neil R., Clarke, Richard W., Devlin, Glyn L., Dobson, Christopher M., Klenerman, David
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567173/
https://ncbi.nlm.nih.gov/pubmed/18796612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803086105
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