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The Evolutionary Selective Advantage of HIV-1 Escape Variants and the Contribution of Escape to the HLA-Associated Risk of AIDS Progression
HIV-1 escape from surveillance by cytotoxic T lymphocytes (CTL) is thought to cause at least transient weakening of immune control. However, the CTL response is highly adaptable and the long-term consequences of viral escape are not fully understood. The objective of this study was to address the qu...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567026/ https://ncbi.nlm.nih.gov/pubmed/18941529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003486 |
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