Effect of human apolipoprotein E genotype on the pathogenesis of experimental ocular HSV-1

The isoform-specific role of human apolipoprotein E (apoE) has been assessed in a mouse model of ocular herpes. Female, age-matched transgenic mice knocked-in for the human allele apoE3 or apoE4 and their parent C57Bl/6 mice were inoculated corneally with HSV-1 strain KOS. Ocular HSV-1 pathogenesis...

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Detalhes bibliográficos
Main Authors: Bhattacharjee, Partha S., Neumann, Donna M., Foster, Timothy P., Bouhanik, Sadallah, Clement, Christian, Vinay, Dass, Thompson, Hilary W., Hill, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566951/
https://ncbi.nlm.nih.gov/pubmed/18572164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2008.05.007
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