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PhoP: A Missing Piece in the Intricate Puzzle of Mycobacterium tuberculosis Virulence

Inactivation of the transcriptional regulator PhoP results in Mycobacterium tuberculosis attenuation. Preclinical testing has shown that attenuated M. tuberculosis phoP mutants hold promise as safe and effective live vaccine candidates. We focused this study to decipher the virulence networks regula...

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Detalhes bibliográficos
Main Authors: Gonzalo-Asensio, Jesús, Mostowy, Serge, Harders-Westerveen, Jose, Huygen, Kris, Hernández-Pando, Rogelio, Thole, Jelle, Behr, Marcel, Gicquel, Brigitte, Martín, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566814/
https://ncbi.nlm.nih.gov/pubmed/18946503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003496
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