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Fetal and Neonatal Nicotine Exposure in Wistar Rats Causes Progressive Pancreatic Mitochondrial Damage and Beta Cell Dysfunction

Nicotine replacement therapy (NRT) is currently recommended as a safe smoking cessation aid for pregnant women. However, fetal and neonatal nicotine exposure in rats causes mitochondrial-mediated beta cell apoptosis at weaning, and adult-onset dysglycemia, which we hypothesize is related to progress...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bruin, Jennifer E., Petre, Maria A., Raha, Sandeep, Morrison, Katherine M., Gerstein, Hertzel C., Holloway, Alison C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566598/
https://ncbi.nlm.nih.gov/pubmed/18852877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003371
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