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Oseltamivir-Resistant Influenza A Viruses Are Transmitted Efficiently among Guinea Pigs by Direct Contact but Not by Aerosol

Influenza viruses resistant to the neuraminidase (NA) inhibitor oseltamivir arise under drug selection pressure both in vitro and in vivo. Several mutations in the active site of the viral NA are known to confer relative resistance to oseltamivir, and influenza viruses with certain oseltamivir resis...

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Autors principals: Bouvier, Nicole M., Lowen, Anice C., Palese, Peter
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566271/
https://ncbi.nlm.nih.gov/pubmed/18684820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01226-08
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