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Possible Role for Cellular Karyopherins in Regulating Polyomavirus and Papillomavirus Capsid Assembly

Polyomavirus and papillomavirus (papovavirus) capsids are composed of 72 capsomeres of their major capsid proteins, VP1 and L1, respectively. After translation in the cytoplasm, L1 and VP1 pentamerize into capsomeres and are then imported into the nucleus using the cellular α and β karyopherins. Vir...

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Detalhes bibliográficos
Main Authors: Bird, Gregory, O'Donnell, Malinda, Moroianu, Junona, Garcea, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566246/
https://ncbi.nlm.nih.gov/pubmed/18701594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01221-08
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