Trade-Off between Iron Uptake and Protection against Oxidative Stress: Deletion of cueO Promotes Uropathogenic Escherichia coli Virulence in a Mouse Model of Urinary Tract Infection

The periplasmic multicopper oxidase (CueO) is involved in copper homeostasis and protection against oxidative stress. Here, we show that the deletion of cueO in uropathogenic Escherichia coli increases its colonization of the urinary tract despite its increased sensitivity to hydrogen peroxide. The...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tree, Jai J., Ulett, Glen C., Ong, Cheryl-Lynn Y., Trott, Darren J., McEwan, Alastair G., Schembri, Mark A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2008
Gaiak:
Molecular Biology of Pathogens
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566202/
https://ncbi.nlm.nih.gov/pubmed/18723628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00451-08
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