Characterization of a Recombinant Newcastle Disease Virus Vaccine Strain

A recombinant La Sota strain (KBNP-C4152R2L) in which fusion (F) and hemagglutinin-neuraminidase (HN) genes were replaced with those of a contemporary genotype VIId virus, KBNP-4152, has been developed. To attenuate the virulence of the recombinant strain, the F cleavage motif was mutated from (112)...

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Autors principals: Cho, Sun-Hee, Kwon, Hyuk-Joon, Kim, Tae-Eun, Kim, Jae-Hong, Yoo, Han-Sang, Park, Man-Hoon, Park, Young-Ho, Kim, Sun-Joong
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Vaccine Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565930/
https://ncbi.nlm.nih.gov/pubmed/18768673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00156-08
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