Limited Inhibitory Effects of Oseltamivir and Zanamivir on Human Sialidases

Oseltamivir (Tamiflu) and zanamivir (Relenza), two extensively used clinically effective anti-influenza drugs, are viral sialidase (also known as neuraminidase) inhibitors that prevent the release of progeny virions and thereby limit the spread of infection. Recently mortalities and neuropsychiatric...

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Bibliographic Details
Main Authors: Hata, Keiko, Koseki, Koichi, Yamaguchi, Kazunori, Moriya, Setsuko, Suzuki, Yasuo, Yingsakmongkon, Sangchai, Hirai, Go, Sodeoka, Mikiko, von Itzstein, Mark, Miyagi, Taeko
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565904/
https://ncbi.nlm.nih.gov/pubmed/18694948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00344-08
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