Activity of the Small Modified Amino Acid α-Hydroxy Glycineamide on In Vitro and In Vivo Human Immunodeficiency Virus Type 1 Capsid Assembly and Infectivity

Upon maturation of the human immunodeficiency virus type 1 (HIV-1) virion, proteolytic cleavage of the Gag precursor protein by the viral protease is followed by morphological changes of the capsid protein p24, which will ultimately transform the virus core from an immature spherical to a mature con...

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Bibliographische Detailangaben
Hauptverfasser: Abdurahman, Samir, Végvári, Ákos, Youssefi, Masoud, Levi, Michael, Höglund, Stefan, Andersson, Elin, Horal, Peter, Svennerholm, Bo, Balzarini, Jan, Vahlne, Anders
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565889/
https://ncbi.nlm.nih.gov/pubmed/18644965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00265-08
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