Genomic Analysis Reveals a Point Mutation in the Two-Component Sensor Gene graS That Leads to Intermediate Vancomycin Resistance in Clinical Staphylococcus aureus

Methicillin-resistant Staphylococcus aureus (MRSA), once restricted to hospitals, is spreading rapidly through the wider community. Resistance to vancomycin, the principal drug used to treat MRSA infections, has only recently emerged, is mainly low level, and characteristically appears during vancom...

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Main Authors: Howden, Benjamin P., Stinear, Timothy P., Allen, David L., Johnson, Paul D. R., Ward, Peter B., Davies, John K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Mechanisms of Resistance
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565880/
https://ncbi.nlm.nih.gov/pubmed/18644967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01613-07
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