rRNA cleavage as an index of ppp(A2'p)nA activity in interferon-treated encephalomyocarditis virus-infected cells.

In cell-free systems, 2-5A [ppp(A2'p)nA, n = 2 to greater than or equal to 4] activates a latent endoribonuclease, the 2-5A-dependent RNase, which cleaves rRNA in intact ribosomes into discrete and characteristic products (D. H. Wreschner et al., Nucleic Acids Res. 9:1571-1581, 1981). Here we presen...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Silverman, R H, Skehel, J J, James, T C, Wreschner, D H, Kerr, I M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1983
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC256583/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6190010/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.46.3.1051-1055.1983
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