Genome-Wide Scan on Total Serum IgE Levels Identifies FCER1A as Novel Susceptibility Locus

High levels of serum IgE are considered markers of parasite and helminth exposure. In addition, they are associated with allergic disorders, play a key role in anti-tumoral defence, and are crucial mediators of autoimmune diseases. Total IgE is a strongly heritable trait. In a genome-wide associatio...

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Autors principals: Weidinger, Stephan, Gieger, Christian, Rodriguez, Elke, Baurecht, Hansjörg, Mempel, Martin, Klopp, Norman, Gohlke, Henning, Wagenpfeil, Stefan, Ollert, Markus, Ring, Johannes, Behrendt, Heidrun, Heinrich, Joachim, Novak, Natalija, Bieber, Thomas, Krämer, Ursula, Berdel, Dietrich, von Berg, Andrea, Bauer, Carl Peter, Herbarth, Olf, Koletzko, Sibylle, Prokisch, Holger, Mehta, Divya, Meitinger, Thomas, Depner, Martin, von Mutius, Erika, Liang, Liming, Moffatt, Miriam, Cookson, William, Kabesch, Michael, Wichmann, H.-Erich, Illig, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565692/
https://ncbi.nlm.nih.gov/pubmed/18846228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000166
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