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Pioglitazone retrieves hepatic antioxidant DNA repair in a mice model of high fat diet

BACKGROUND: Pioglitazone was reported to improve hepatic steatosis and necroinflammation in human studies. To investigate whether the hepato-protective effect of pioglitazone was associated with an improvement of antioxidant defense mechanism, oxidative DNA damage and repair activity were determined...

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Detalhes bibliográficos
Main Authors: Hsiao, Pi-Jung, Hsieh, Tusty-Jiuan, Kuo, Kung-Kai, Hung, Wei-Wen, Tsai, Kun-Bow, Yang, Ching-Hsiu, Yu, Ming-Lung, Shin, Shyi-Jang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565677/
https://ncbi.nlm.nih.gov/pubmed/18822121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-82
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