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Mutational optimization of the coelenterazine-dependent luciferase from Renilla

Renilla luciferase (RLUC) is a popular reporter enzyme for gene expression and biosensor applications, but it is an unstable enzyme whose catalytic mechanism remains to be elucidated. We titrated that one RLUC molecule can turn over about one hundred molecules of coelenterazine substrate. Mutagenesi...

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Detalhes bibliográficos
Main Authors: Woo, Jongchan, von Arnim, Albrecht G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565673/
https://ncbi.nlm.nih.gov/pubmed/18826616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-4811-4-23
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