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Thermolabile in vivo DNA-binding activity associated with a protein encoded by mutants of herpes simplex virus type 1.

The major DNA-binding protein encoded by several temperature-sensitive mutants of herpes simplex virus type 1 was thermolabile for binding to intracellular viral DNA. The ability of DNase I to release this protein from isolated nuclei was used as a measure of the amount of protein bound to viral DNA...

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Bibliographic Details
Published in:J Virol
Main Authors: Lee, C K, Knipe, D M
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1983
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC256566/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6304350/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.46.3.909-919.1983
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