Anti-HIV-1 Response Elicited in Rabbits by Anti-Idiotype Monoclonal Antibodies Mimicking the CD4-Binding Site

Antibodies against conserved epitopes on HIV-1 envelope glycoproteins (Env), such as the gp120 CD4-binding site (CD4bs), could contribute to protection against HIV-1. Env-based immunogens inducing such a response could be a major component of future anti-HIV-1 strategies. In this proof-of-concept st...

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Autori principali: Burioni, Roberto, Mancini, Nicasio, De Marco, Donata, Clementi, Nicola, Perotti, Mario, Nitti, Giovanni, Sassi, Monica, Canducci, Filippo, Shvela, Krisha, Bagnarelli, Patrizia, Mascola, John R., Clementi, Massimo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565497/
https://ncbi.nlm.nih.gov/pubmed/18923648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003423
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