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Site-directed deletions of Abelson murine leukemia virus define 3' sequences essential for transformation and lethality.

Abelson murine leukemia virus (A-MuLV) encodes a single protein with tyrosine kinase activity that can transform fibroblast cell lines in vitro and lymphoid target cells in vitro and in vivo. Expression of kinase-active A-MuLV protein can result in a deleterious effect on transformed fibroblast popu...

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Bibliographic Details
Main Authors: Watanabe, S M, Witte, O N
Format: Artigo
Language:Inglês
Published: 1983
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC256510/
https://ncbi.nlm.nih.gov/pubmed/6300444
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