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Sensory signalling effects of tegaserod in patients with irritable bowel syndrome with constipation

Tegaserod relieves overall and multiple individual constipation-predominant IBS (IBS-C) symptoms. However, mechanisms for the relief of abdominal pain/discomfort are not well understood. The effects of tegaserod on rectal sensitivity to distension were measured by the nociceptive flexion RIII reflex...

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Main Authors: Sabaté, Jean-Marc, Bouhassira, Didier, Poupardin, Cécile, Wagner, Amy, Loria, Yolande, Coffin, Benoit
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Scientific Publications 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564990/
https://ncbi.nlm.nih.gov/pubmed/18004988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2007.01030.x
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