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Individual disease risk and multimetric analysis of Crohn disease
Rare dominant genes with high penetrance can be identified by linkage without inbreeding, whereas rare recessive genes with high penetrance are most efficiently recognized by autozygosity mapping of homozygotes in pedigrees with preferential inbreeding. On the contrary, complex inheritance is charac...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2564981/ https://ncbi.nlm.nih.gov/pubmed/18843111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808009105 |
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