A chemical-genetic strategy reveals distinct temporal requirements for SAD-1 kinase in neuronal polarization and synapse formation

BACKGROUND: Neurons assemble into a functional network through a sequence of developmental processes including neuronal polarization and synapse formation. In Caenorhabditis elegans, the serine/threonine SAD-1 kinase is essential for proper neuronal polarity and synaptic organization. To determine i...

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Autores principales: Kim, Joanne SM, Lilley, Brendan N, Zhang, Chao, Shokat, Kevan M, Sanes, Joshua R, Zhen, Mei
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564922/
https://ncbi.nlm.nih.gov/pubmed/18808695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8104-3-23
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