Exhaled and arterial levels of endothelin-1 are increased and correlate with pulmonary systolic pressure in COPD with pulmonary hypertension

BACKGROUND: Endothelin-1 (ET-1) and Nitric Oxide (NO) are crucial mediators for establishing pulmonary artery hypertension (PAH). We tested the hypothesis that their imbalance might also occur in COPD patients with PAH. METHODS: The aims of the study were to measure exhaled breath condensate (EBC) a...

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Detalhes bibliográficos
Main Authors: Carratu, Pierluigi, Scoditti, Cristina, Maniscalco, Mauro, Seccia, Teresa Maria, Di Gioia, Giuseppe, Gadaleta, Felice, Cardone, Rosa Angela, Dragonieri, Silvano, Pierucci, Paola, Spanevello, Antonio, Resta, Onofrio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564898/
https://ncbi.nlm.nih.gov/pubmed/18822124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-8-20
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