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Mechanism of UV-related carcinogenesis and its contribution to nevi/melanoma
Melanoma consists 4–5 % of all skin cancers, but it contributes to 71–80 % of skin cancers deaths. UV light affects cell and tissue homeostasis due to its damaging effects on DNA integrity and modification of expression of a plethora of genes. DNA repair systems protect cells from UV-induced lesions...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2564815/ https://ncbi.nlm.nih.gov/pubmed/18846265 |
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