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Fumarate hydratase enzyme activity in lymphoblastoid cells and fibroblasts of individuals in families with hereditary leiomyomatosis and renal cell cancer

BACKGROUND: Hereditary leiomyomatosis and renal cell cancer (HLRCC) is the autosomal dominant heritable syndrome with predisposition to development of renal cell carcinoma and smooth muscle tumours of the skin and uterus. OBJECTIVE: To measure the fumarate hydratase (FH) enzyme activity in lymphobla...

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Autors principals: Pithukpakorn, M, Wei, M‐H, Toure, O, Steinbach, P J, Glenn, G M, Zbar, B, Linehan, W M, Toro, J R
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564577/
https://ncbi.nlm.nih.gov/pubmed/16597677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.041087
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