Polymorphisms in the VKORC1 gene are strongly associated with warfarin dosage requirements in patients receiving anticoagulation

BACKGROUND: Warfarin is a mainstay of therapy for conditions associated with an increased risk of thromboembolic events. However, the use of this common agent is fraught with complications and little is known regarding inter‐individual variation in warfarin response. OBJECTIVE: We tested for associa...

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Bibliografiske detaljer
Main Authors: Li, T, Lange, L A, Li, X, Susswein, L, Bryant, B, Malone, R, Lange, E M, Huang, T‐Y, Stafford, D W, Evans, J P
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Group 2006
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564574/
https://ncbi.nlm.nih.gov/pubmed/16611750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2005.040410
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