A common nonsense mutation in EphB2 is associated with prostate cancer risk in African American men with a positive family history

BACKGROUND: The EphB2 gene was recently implicated as a prostate cancer (PC) tumour suppressor gene, with somatic inactivating mutations occurring in ∼10% of sporadic tumours. We evaluated the contribution of EphB2 to inherited PC susceptibility in African Americans (AA) by screening the gene for ge...

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Detalhes bibliográficos
Main Authors: Kittles, R A, Baffoe‐Bonnie, A B, Moses, T Y, Robbins, C M, Ahaghotu, C, Huusko, P, Pettaway, C, Vijayakumar, S, Bennett, J, Hoke, G, Mason, T, Weinrich, S, Trent, J M, Collins, F S, Mousses, S, Bailey‐Wilson, J, Furbert‐Harris, P, Dunston, G, Powell, I J, Carpten, J D
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564535/
https://ncbi.nlm.nih.gov/pubmed/16155194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2005.035790
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