Analysis of RUNX1 binding site and RAPTOR polymorphisms in psoriasis: no evidence for association despite adequate power and evidence for linkage

BACKGROUND: A previous study identified two peaks of allelic association between psoriasis and single nucleotide polymorphisms (SNPs) mapping to distal chromosome 17q, including a disease associated SNP that leads to loss of a RUNX1 transcription factor binding site, and additional SNPs in the third...

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Bibliografiska uppgifter
Huvudupphovsmän: Stuart, P, Nair, R P, Abecasis, G R, Nistor, I, Hiremagalore, R, Chia, N V, Qin, Z S, Thompson, R A, Jenisch, S, Weichenthal, M, Janiga, J, Lim, H W, Christophers, E, Voorhees, J J, Elder, J T
Materialtyp: Artigo
Språk:Inglês
Publicerad: BMJ Group 2006
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564497/
https://ncbi.nlm.nih.gov/pubmed/15923274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2005.032193
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