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An SNP in protamine 1: a possible genetic cause of male infertility?
Gene targeting of the sperm nuclear proteins, the protamines, in mice leads to haploinsufficiency, abnormal chromatin compaction, sperm DNA damage, and male infertility. In order to investigate whether changes in amount or structure of the protamines could be a cause of human infertility, we sequenc...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BMJ Group
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2563215/ https://ncbi.nlm.nih.gov/pubmed/16199539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2005.037168 |
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