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Angiotensinogen and transforming growth factor β1: novel genes in the pathogenesis of Crohn's disease

BACKGROUND: Angiotensin peptides may act locally as cytokines in several organ systems with elevated mucosal levels present in Crohn's disease. A variant in the angiotensinogen gene promoter results in increased peptide production, while transforming growth factor β1 (TGFβ1) codon 25 variants d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hume, G E, Fowler, E V, Lincoln, D, Eri, R, Templeton, D, Florin, T H, Cavanaugh, J A, Radford‐Smith, G L
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Group 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563170/
https://ncbi.nlm.nih.gov/pubmed/17047091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2005.040477
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