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Bioinformatics identification of MurJ (MviN) as the peptidoglycan lipid II flippase in Escherichia coli

Peptidoglycan is a cell-wall glycopeptide polymer that protects bacteria from osmotic lysis. Whereas in Gram-positive bacteria it also serves as scaffold for many virulence factors, in Gram-negative bacteria, peptidoglycan is an anchor for the outer membrane. For years, we have known the enzymes req...

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Bibliographic Details
Main Author: Ruiz, Natividad
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563115/
https://ncbi.nlm.nih.gov/pubmed/18832143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808352105
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