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The role of the C terminus of the SNARE protein SNAP-25 in fusion pore opening and a model for fusion pore mechanics

Formation of a fusion pore between a vesicle and its target membrane is thought to involve the so-called SNARE protein complex. However, there is no mechanistic model explaining how the fusion pore is opened by conformational changes in the SNARE complex. It has been suggested that C-terminal zippin...

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Detalhes bibliográficos
Main Authors: Fang, Qinghua, Berberian, Khajak, Gong, Liang-Wei, Hafez, Ismail, Sørensen, Jakob B., Lindau, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563113/
https://ncbi.nlm.nih.gov/pubmed/18829435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805377105
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