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Blood–brain barrier changes and cell invasion differ between therapeutic immune clearance of neurotrophic virus and CNS autoimmunity

CNS tissues are protected from circulating cells and factors by the blood–brain barrier (BBB), a specialization of the neurovasculature. Outcomes of the loss of BBB integrity and cell infiltration into CNS tissues can differ vastly. For example, elevated BBB permeability is closely associated with t...

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Detalhes bibliográficos
Main Authors: Fabis, Marzena J., Phares, Timothy W., Kean, Rhonda B., Koprowski, Hilary, Hooper, D. Craig
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563072/
https://ncbi.nlm.nih.gov/pubmed/18829442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807656105
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