Notch1 regulates the fate of cardiac progenitor cells

The Notch receptor mediates cell fate decision in multiple organs. In the current work we tested the hypothesis that Nkx2.5 is a target gene of Notch1 and raised the possibility that Notch1 regulates myocyte commitment in the adult heart. Cardiac progenitor cells (CPCs) in the niches express Notch1...

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Hlavní autoři: Boni, Alessandro, Urbanek, Konrad, Nascimbene, Angelo, Hosoda, Toru, Zheng, Hanqiao, Delucchi, Francesca, Amano, Katsuya, Gonzalez, Arantxa, Vitale, Serena, Ojaimi, Caroline, Rizzi, Roberto, Bolli, Roberto, Yutzey, Katherine E., Rota, Marcello, Kajstura, Jan, Anversa, Piero, Leri, Annarosa
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563067/
https://ncbi.nlm.nih.gov/pubmed/18832173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808357105
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