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A single site for N-linked glycosylation in the envelope glycoprotein of feline immunodeficiency virus modulates the virus-receptor interaction

Feline immunodeficiency virus (FIV) targets helper T cells by attachment of the envelope glycoprotein (Env) to CD134, a subsequent interaction with CXCR4 then facilitating the process of viral entry. As the CXCR4 binding site is not exposed until CD134-binding has occurred then the virus is protecte...

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Hlavní autoři: Willett, Brian J, McMonagle, Elizabeth L, Logan, Nicola, Samman, Ayman, Hosie, Margaret J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2563026/
https://ncbi.nlm.nih.gov/pubmed/18721458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-5-77
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