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The Plasmid Replicon of Epstein-Barr Virus: Mechanistic Insights Into Efficient, Licensed, Extrachromosomal Replication in Human Cells

The genome of Epstein-Barr Virus (EBV) and plasmid derivatives of it are among the most efficient extrachromosomal replicons in mammalian cells. The latent origin of plasmid replication (oriP), when supplied with the viral Epstein-Barr Nuclear Antigen 1 (EBNA1) in trans, provides efficient duplicati...

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Detalhes bibliográficos
Main Authors: Lindner, Scott E., Sugden, Bill
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562867/
https://ncbi.nlm.nih.gov/pubmed/17350094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plasmid.2007.01.003
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