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Induction of Incomplete Autophagic Response by Hepatitis C Virus via the Unfolded Protein Response

Autophagy is important for cellular homeostasis and can serve as innate immunity to remove intracellular pathogens. Here we demonstrate by a battery of morphological and biochemical assays that HCV induces the accumulation of autophagosomes in cells without enhancing autophagic protein degradation....

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Main Authors: Sir, Donna, Chen, Wen-ling, Choi, Jinah, Wakita, Takaji, Yen, T.S. Benedict, Ou, Jing-hsiung James
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562598/
https://ncbi.nlm.nih.gov/pubmed/18688877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22464
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