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Central memory CD8(+) T cells have a shorter lifespan and reduced abundance as a function of HIV disease progression

Progressive HIV disease has been associated with loss of memory T cell responses to antigen. To better characterize and quantify long-lived memory T cells in vivo, we have refined an in vivo labeling technique to study the kinetics of phenotypically distinct, low frequency CD8(+) T cell subpopulatio...

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Bibliografiska uppgifter
Huvudupphovsmän: Ladell, Kristin, Hellerstein, Marc K., Cesar, Denise, Busch, Robert, Boban, Drina, McCune, Joseph M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562545/
https://ncbi.nlm.nih.gov/pubmed/18523254
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