Control of Parasitophorous Vacuole Expansion by LYST/Beige Restricts the Intracellular Growth of Leishmania amazonensis

The intracellular protozoan Leishmania replicates in parasitophorous vacuoles (PV) that share many features with late endosomes/lysosomes. L. amazonensis PVs expand markedly during infections, but the impact of PV size on parasite intracellular survival is still unknown. Here we show that host cells...

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Main Authors: Wilson, Jude, Huynh, Chau, Kennedy, Kathleen A., Ward, Diane M., Kaplan, Jerry, Aderem, Alan, Andrews, Norma W.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2008
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562527/
https://ncbi.nlm.nih.gov/pubmed/18927622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000179
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