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Nonselective suppression of operant ethanol and sucrose self-administration by the mGluR7 positive allosteric modulator AMN082

Emerging evidence indicates that specific metabotropic glutamate receptors (mGluRs) modulate ethanol self-administration. In general, inhibition of glutamate transmission through blockade of postsynaptic mGluRs, or activation of presynaptic mGluRs, inhibits ethanol self-administration. The goal of t...

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Bibliographic Details
Main Authors: Salling, Michael C., Faccidomo, Sara, Hodge, Clyde W.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562464/
https://ncbi.nlm.nih.gov/pubmed/18593591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2008.06.006
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