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PEDF-Deficient Mice Exhibit an Enhanced Rate of Retinal Vascular Expansion and are More Sensitive to Hyperoxia-Mediated Vessel Obliteration

Pigment epithelium derived factor (PEDF) is an endogenous inhibitor of angiogenesis. However, its physiological role during vascular development and neovascularization remains elusive. Here we investigated the role of PEDF in normal postnatal vascularization of retina and retinal neovascularization...

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Autors principals: Huang, Qiong, Wang, Shoujian, Sorenson, Christine M., Sheibani, Nader
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562453/
https://ncbi.nlm.nih.gov/pubmed/18602915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2008.06.003
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