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Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood
We directly sequenced cell-free DNA with high-throughput shotgun sequencing technology from plasma of pregnant women, obtaining, on average, 5 million sequence tags per patient sample. This enabled us to measure the over- and underrepresentation of chromosomes from an aneuploid fetus. The sequencing...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2562413/ https://ncbi.nlm.nih.gov/pubmed/18838674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808319105 |
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