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Roles for Loop 2 Residues of α1 Glycine Receptors in Agonist Activation

The present study tested the hypothesis that several residues in Loop 2 of α1 glycine receptors (GlyRs) play important roles in mediating the transduction of agonist activation to channel gating. This was accomplished by investigating the effect of cysteine point mutations at positions 50–60 on glyc...

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Detalhes bibliográficos
Main Authors: Crawford, Daniel K., Perkins, Daya I., Trudell, James R., Bertaccini, Edward J., Davies, Daryl L., Alkana, Ronald L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562068/
https://ncbi.nlm.nih.gov/pubmed/18658152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802384200
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